Capped at both termini
N-acetyl + C-amide block both peptidase classes.
FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from peer-reviewed literature for educational reference.
Neuropeptide
N-Acetyl Selank (Amidated)
- NA-Selank
- Selank amidate
- NASA Selank
- N-Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH₂
CAS: 129954-34-3
Acetylated + C-terminally amidated analog of Selank engineered to resist enzymatic degradation, used in research on stress-response, GABAergic neurotransmission, and BDNF expression with extended half-life vs the parent peptide.
CoA available on request
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Extended half-life
Substantially longer than the ~2-3 min parent peptide.
99%+ identity purity
HPLC + MS verified per batch. CoA included.
What Is N-Acetyl Selank (Amidated)?
N-Acetyl Selank is a synthetic derivative of the heptapeptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) in which the N-terminus has been acetylated and the C-terminal proline converted to a primary amide. Both modifications block the principal degradation pathways (aminopeptidases at the N-terminus, carboxypeptidases at the C-terminus) that limit native Selank to a ~2-3 minute plasma half-life. Pharmacodynamic activity at GABAergic, serotonergic, and BDNF-expression pathways is preserved; the modifications are pharmacokinetic rather than pharmacological.
Technical specifications
Type
Synthetic acetylated heptapeptide amide
Formula
C₃₅H₆₀N₁₂O₁₀ (estimated)
Molecular weight
792.94 g/mol (estimated)
CAS number
129954-34-3
Appearance
White lyophilized powder
Identity purity
≥ 99% (HPLC + MS)
Peer-reviewed research
- Bull Exp Biol MedComparison of pharmacological effects of heptapeptide Selank after intranasal and intraperitoneal administration to BALB/c and C57BL/6 mice
- Bull Exp Biol MedSelank as a regulator of expression of monoamine system genes in rat brain
Frequently researched together
IMPORTANT RESEARCH NOTICE
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.