FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from peer-reviewed literature for educational reference.
Cellular Peptide

SS-31

  • Elamipretide
  • MTP-131
  • Bendavia

CAS: 736992-21-5

A mitochondrially-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH₂) studied for cardiolipin stabilization and inner-mitochondrial-membrane integrity in cellular and animal research.

SS-31
  • Free shipment protection
  • Free shipping on $250+
  • Damage protection
  • 256-bit SSL checkout

Mitochondrial localization

Binds cardiolipin in inner mitochondrial membrane.

Bioenergetic recovery

Studied in ischemia, heart failure, and mito disease.

99%+ identity purity

HPLC + MS verified per batch. CoA included.

MOLECULAR PROFILE

What Is SS-31?

SS-31 (Elamipretide) is a Szeto-Schiller tetrapeptide that selectively localizes to the inner mitochondrial membrane via electrostatic and hydrophobic interaction with cardiolipin. Research has examined its effects on mitochondrial respiration, ROS production, cristae morphology, and bioenergetic recovery in models of ischemia-reperfusion, heart failure, and mitochondrial disease.

COMPOUND INFORMATION

Technical specifications

Type
Synthetic tetrapeptide
Formula
C₃₂H₄₉N₉O₅
Molecular weight
639.78 g/mol
CAS number
736992-21-5
Appearance
White lyophilized powder
Identity purity
≥ 99% (HPLC + MS)
SOURCES & REFERENCES

Peer-reviewed research

  1. Br J Pharmacol
    First-in-class cardiolipin-protective compound to restore mitochondrial bioenergetics in preclinical models
    2014· PMID: 24506346View on PubMed →
    Szeto HH
  2. Aging Cell
    Mitochondrial-targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice
    2013· PMID: 23647593View on PubMed →
    Siegel MP, Kruse SE, Percival JM et al.
View all related research on PubMed
RELATED RESEARCH

Frequently researched together

IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.