Mitochondrial localization
Binds cardiolipin in inner mitochondrial membrane.
CAS: 736992-21-5
A mitochondrially-targeted tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH₂) studied for cardiolipin stabilization and inner-mitochondrial-membrane integrity in cellular and animal research.

Binds cardiolipin in inner mitochondrial membrane.
Studied in ischemia, heart failure, and mito disease.
HPLC + MS verified per batch. CoA included.
SS-31 (Elamipretide) is a Szeto-Schiller tetrapeptide that selectively localizes to the inner mitochondrial membrane via electrostatic and hydrophobic interaction with cardiolipin. Research has examined its effects on mitochondrial respiration, ROS production, cristae morphology, and bioenergetic recovery in models of ischemia-reperfusion, heart failure, and mitochondrial disease.
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