FOR RESEARCH PURPOSES ONLY — Not for human or veterinary use. Citations describe published research and do not establish this product’s identity, purity, safety, or effects.
Metabolic Peptide

MOTS-c

  • Mitochondrial ORF of 12S rRNA type-c
  • MRWQEMGYIFYPRKLR

A mitochondrial-derived 16-residue peptide encoded within the 12S rRNA gene, studied for AMPK activation, glucose homeostasis, and exercise-metabolism research.

MOTS-c
$130.00$90.00/ vial
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MOTS-c$130.00$90.00

Mitochondrial origin

16-residue peptide encoded within 12S rRNA.

AMPK signaling

Studied in glucose homeostasis and exercise models.

Batch documentation

Review available batch-specific analytical records.

MOLECULAR PROFILE

What Is MOTS-c?

MOTS-c is a mitochondrial-derived peptide (MDP) encoded by an open reading frame within the 12S ribosomal RNA gene. Research has investigated its role as a regulator of AMPK signaling, glucose uptake, insulin sensitivity, exercise capacity, and aging-related metabolic decline in cell and animal models.

COMPOUND INFORMATION

Technical specifications

Type
Mitochondrial-derived peptide
Formula
C₁₀₂H₁₅₃N₂₇O₂₃S₂
Molecular weight
2174.5 g/mol
Appearance
White lyophilized powder
Analytical documentation
Refer to available batch-specific analytical records.
FAQ

MOTS-c — common research questions

Straight answers for researchers comparing purity, CoA documentation, kits, and shipping.

Is MOTS-c for research use only?

Yes. Vorix Labs materials are sold for laboratory / in-vitro research only, not for human or veterinary use or clinical applications.

Where can I find a CoA for MOTS-c?

Use the product page’s View CoA PDF link or the CoA library to open the report hosted on this website. Check the sample, analysis date and actual measured results in the PDF. Contact us if you need to confirm which report applies to the stock you are ordering.

What package sizes are available for MOTS-c?

The catalog lists 40 mg per vial. Select single vials or a kit of 10 in the product selector. A kit contains 10 vials of the selected product and strength; availability and the current total are shown before adding to cart.

Where do orders ship from?

Orders ship from our US warehouse. See the shipping page for processing times, available services and current charges; the checkout displays the applicable shipping options.

SOURCES & REFERENCES

Peer-reviewed research

  1. Cell Metab
    The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.
    2015· DOI: 10.1016/j.cmet.2015.02.009· PMID: 25738459View on PubMed →
    Lee C, Zeng J, Drew BG et al.

    MOTS-c experiments in cell and mouse models.

  2. Nat Commun
    MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.
    2021· DOI: 10.1038/s41467-020-20790-0· PMID: 33473109View on PubMed →
    Reynolds JC, Lai RW, Woodhead JST et al.

    MOTS-c experiments in mice and measurements of endogenous MOTS-c in humans; not testing of this product.

View all related research on PubMed
RELATED RESEARCH

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IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.