Mitochondrial origin
Encoded by 12S rRNA — the original MDP.
FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from peer-reviewed literature for educational reference.
Metabolic Peptide
MOTS-c
- Mitochondrial ORF of 12S rRNA type-c
- MRWQEMGYIFYPRKLR
A mitochondrial-derived 16-residue peptide encoded within the 12S rRNA gene, studied for AMPK activation, glucose homeostasis, and exercise-metabolism research.
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AMPK signaling
Studied in glucose homeostasis and exercise models.
99%+ identity purity
HPLC + MS verified per batch. CoA included.
What Is MOTS-c?
MOTS-c is a mitochondrial-derived peptide (MDP) encoded by an open reading frame within the 12S ribosomal RNA gene. Research has investigated its role as a regulator of AMPK signaling, glucose uptake, insulin sensitivity, exercise capacity, and aging-related metabolic decline in cell and animal models.
Technical specifications
Type
Mitochondrial-derived peptide
Formula
C₁₀₂H₁₅₃N₂₇O₂₃S₂
Molecular weight
2174.5 g/mol
Appearance
White lyophilized powder
Identity purity
≥ 99% (HPLC + MS)
Peer-reviewed research
- Cell MetabThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance
- Aging CellMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Frequently researched together
IMPORTANT RESEARCH NOTICE
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.