Minimal active fragment
Three residues — retains α-MSH anti-inflam activity.
FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from peer-reviewed literature for educational reference.
Dermal Compound
KPV
- Lysine-Proline-Valine
- α-MSH (11-13)
- α-MSH C-Terminal Fragment
CAS: 67727-97-3
A three-residue C-terminal fragment of alpha-MSH (Lys-Pro-Val) studied for anti-inflammatory effects in models of dermal, ocular, and gastrointestinal inflammation.
- Free shipment protection
- Free shipping on $250+
- Damage protection
- 256-bit SSL checkout
NF-κB modulation
Studied in IBD, dermatitis, and ocular models.
99%+ identity purity
HPLC + MS verified per batch. CoA included.
What Is KPV?
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH). It retains alpha-MSH's anti-inflammatory activity in a minimal sequence, with mechanistic studies pointing to NF-κB suppression and modulation of mast-cell degranulation. Used in research models of inflammatory bowel disease, dermatitis, and ocular inflammation.
Technical specifications
Type
Synthetic tripeptide
Formula
C₁₆H₃₀N₄O₄
Molecular weight
342.43 g/mol
CAS number
67727-97-3
Appearance
White lyophilized powder
Identity purity
≥ 99% (HPLC + MS)
Peer-reviewed research
- GastroenterologyThe tripeptide KPV reduces inflammation in murine and human colitis
- J Investig Dermatol Symp ProcAlpha-melanocyte-stimulating hormone in cutaneous biology
Frequently researched together
IMPORTANT RESEARCH NOTICE
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.