FOR RESEARCH PURPOSES ONLY — Not for human or veterinary use. Citations describe published research and do not establish this product’s identity, purity, safety, or effects.
Growth Factor

IGF-1 LR3

  • Long R3 IGF-1
  • LR3 IGF-1
  • rh-IGF-1 LR3

CAS: 143045-27-6

An engineered analogue of insulin-like growth factor 1 with reduced binding-protein affinity, used in experimental studies of IGF signaling and growth-factor biology.

IGF-1 LR3
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IGF-1 LR3$100.00$70.00

IGF-I analogue

R3 substitution and 13-residue N-terminal extension.

Binding-protein research

Model-dependent IGF and IGFBP interactions.

Batch documentation

Review available batch-specific analytical records.

MOLECULAR PROFILE

What Is IGF-1 LR3?

IGF-1 LR3, also called Long R3 IGF-I, is an 83-amino-acid analogue with a 13-residue N-terminal extension and an arginine substitution at position 3 of the IGF-I sequence. Published work has examined its reduced interaction with IGF binding proteins and its model-dependent biological effects. The cited pig study and general binding-protein review do not establish a circulating half-life for this product.

COMPOUND INFORMATION

Technical specifications

Type
Recombinant 83-amino-acid IGF-1 analogue
Formula
C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
Molecular weight
9111.45 g/mol
CAS number
143045-27-6
Appearance
White lyophilized powder
Analytical documentation
Refer to available batch-specific analytical records.
FAQ

IGF-1 LR3 — common research questions

Straight answers for researchers comparing purity, CoA documentation, kits, and shipping.

Is IGF-1 LR3 for research use only?

Yes. Vorix Labs materials are sold for laboratory / in-vitro research only, not for human or veterinary use or clinical applications.

Where can I find a CoA for IGF-1 LR3?

COA currently unavailable. Contact our team before ordering if your procurement process requires a report for this material. Reports for other products are available in the CoA library.

What package sizes are available for IGF-1 LR3?

The catalog lists 1 mg per vial. Select single vials or a kit of 10 in the product selector. A kit contains 10 vials of the selected product and strength; availability and the current total are shown before adding to cart.

Where do orders ship from?

Orders ship from our US warehouse. See the shipping page for processing times, available services and current charges; the checkout displays the applicable shipping options.

SOURCES & REFERENCES

Peer-reviewed research

  1. J Endocrinol
    Long [R3] insulin-like growth factor-I reduces growth, plasma growth hormone, IGF binding protein-3 and endogenous IGF-I concentrations in pigs.
    1997· DOI: 10.1677/joe.0.1550559· PMID: 9488001View on PubMed →
    Dunaiski V, Dunshea FR, Walton PE et al.

    Long R3 IGF-I study in pigs; effects in this animal model do not establish this product’s pharmacokinetics.

  2. Endocr Rev
    Signaling Pathways of the Insulin-like Growth Factor Binding Proteins.
    2023· DOI: 10.1210/endrev/bnad008· PMID: 36974712View on PubMed →
    Baxter RC

    General review of IGF binding-protein signaling; not a direct study of IGF-1 LR3 or this product.

View all related research on PubMed
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IMPORTANT RESEARCH NOTICE

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.